Globalization and economic integration are all-encompassing. Even sincere and active supporters of globalization, including myself, should recognize that everything has two sides. Globalization can also be an illegal activity, such as drug or human trafficking, and the cross-border movement of people is the spread of disease. Create opportunities. Comparing the speed of transmission of early infectious diseases, bird flu and the recent new coronary pneumonia have evolved into a global pandemic in just 2 months. To control the global spread of the new crown epidemic, international cooperation is needed. However, in practice, it may be used as a tool to limit economic ties between countries and as an excuse for protectionism. In the book "Eurasian Integration: Challenges of Trans-continental Regionalism" published in 2012, we put forward a major assumption, which is to move towards the Eurasian Common Market on the basis of the development of public infrastructure construction. Advancing will bring significant economic benefits. But at the same time, we also emphasize that addressing common threats, especially drug smuggling, human smuggling, and the threat of cross-border epidemics, should go hand in hand with a positive integration agenda. Overall, the double-edged sword of globalization has also brought new challenges to these regions, and put new requirements on government governance capabilities and international cooperation. We should focus on emerging issues. For example, after the September 11 terrorist attacks, drug and arms trafficking has become the focus of public debate. In the past decade, from SARS to enterohemorrhagic E. coli (EHEC), A number of epidemic threats have emerged in Eurasia. However, due to misunderstandings and lack of appropriate information, decision-making by public institutions is often hampered. Often, the line between actual and potential threats is very delicate. Current international cooperation is not enough. Although all countries recognize the importance of these issues (at least verbally), they often fail to respond appropriately, as some administrative bureaucracies limit effective responses. A very typical response to human trafficking, illegal immigration and epidemics is to strengthen border controls. However, this limits economic exchanges and could have disastrous consequences. These consequences are not only limited by the potential for growth, but also reflected in the limited economic exchanges between Eurasian countries. Although successfully addressing the "negative aspects" of regionalization, they have also led to the promotion of economic development and the reduction of Hopes for poverty rates in poor areas have become increasingly slim. The new crown pneumonia crisis makes it very clear that it is time to strengthen international cooperation in this area. These cooperations are not limited to the actions of the World Health Organization but also support from other forces.